主要研究方向:
1.生态/健康风险评价
2.地下水污染监测与评价
3.污染物暴露与危害机理研究
4.污染物控制与修复机理研究
代表性论文:
1. Jian Li, Yun Liu, Rui Zuo, Yanguo Teng, Yang Ai, Jie Yang. Influences of dissolved humic acid on Zn bioavailability and its consequences for thyroid toxicity. Ecotoxicology and Environment Safety, 2018(166):132-137.
2. Dongdong Kong, Yun Liu, Rui Zuo, Jian Li*. DnBP-induced thyroid disrupting activities in GH3 cells via integrin avβ3 and ERK1/ 2 activation. Chemosphere, 2018(212):1058-1066.
3. Yang Shen, Dongdong Kong, Yanguo Teng, Yafei Wang, Jian Li*. An assessment of the presence and health risks of endocrine disrupting chemicals in the drinking water treatment plant of Wu Chang, China. Human and Ecological Risk Assessment, 2018(24):1127-1137.
4. Jian Li, Yun Liu, Dongdong Kong, Shujuan Ren, Na Li. T-screen and yeast assay for the detection of the thyroid-disrupting activities of cadmium, mercury and zinc. Environmental Science and Pollution Research, 2016, 23 (10), 9843–9851.
5. Dongdong Kong, Yafei Wang, Jinsheng Wang, Yanguo Teng, Na Li, and Jian Li*. Evaluation and characterization of thyroid-disrupting activities in soil samples along the Second Songhua River, China. Ecotoxicology and Environment Safety, 2016, 133:475-480.
6. Jian Li*, Yafei Wang, Dongdong Kong, Jinsheng Wang, Yanguo Teng, Na Li. Evaluation and Characterization of Anti/estrogenin and Anti/androgenic activities in Soil Samples along the Second Songhua River, China. Environmental Monitoring and Assessment, 2015, 187(11), 724-734.
7. Jian Li*, Shujuan Ren, Shaolun Han, Na Li. A Yeast Bioassay for Direct Measurement of Thyroid Hormone Disrupting Effects in Water without Sample Extraction, Concentration, or Sterilization. Chemosphere, 2014, 100, 139-145.
8. Jian Li*, Shujuan Ren, Shaolun Han, Bingli Lei, Na Li. Identification of Thyroid Receptor Antagonists in Water from the Guanting Reservoir, Beijing, China. Archives of Environmental Contamination Toxicology, 2014, 67(1), 68-77.
9. Jian Li*, Morui Li, Shujuan Ren, Chenglian Feng, Na Li. Thyroid Hormone Disrupting Activities of Sediment from the Guanting Reservoir, Beijing, China. Journal of Hazardous Materials, 2014, 274, 191-197.
10. Jian Li*, Ming Chen, Zijian Wang, Mei Ma, Xianzhi Peng. Analysis of Environmental Endocrine Disrupting Activities in Wastewater Treatment Plant Effluents Using Recombinant Yeast Assays Incorporated with Exogenous Metabolic Activation System. Biomedical and Environmental Sciences, 2011, 24(2), 132-139.
11. Jian Li, Zijian Wang, Mei Ma, Xianzhi Peng. Analysis of Environmental Endocrine Disrupting Activities Using Recombinant Yeast Assay in Wastewater Treatment Plant Effluents. Bulletin of Environmental Contamination and Toxicology, 2010, 84(5), 529–535.
12. Jian Li, Mei Ma, Zijian Wang. In Vitro Profiling of Endocrine Disrupting Effects of Phenols. Toxicology in Vitro, 2010, 24(1), 201-207.
13. Jian Li, Mei Ma, Zijian Wang. A Two-hybrid Yeast Assay to Quantify the Effects of Xenobotics on Thyroid Hormone-mediated Gene Expression. Environmental Toxicology and Chemistry, 2008, 27(1),159-167.
14. Jian Li, Mei Ma, Zijian Wang. A Two-hybrid Yeast Assay to Quantify the Effects of Xenobiotics on Retinoid X Receptor -mediated Gene Expression. Toxicology Letters, 2008, 176 (3), 198-206.
15. Jian Li, Mei Ma, Qing Cui, Zijian Wang. Assessing the Potential Risk of Oil-field Produced Waters Using a Battery of Bioassays/Biomarkers. Bulletin of Environmental Contamination and Toxicology, 2008, 80 (6), 492-496.
16. Jian Li, Mei Ma, John P Giesy, Zijian Wang. In Vitro Profling of the Endocrine Disrupting Potency of Organochlorine Pesticides. Toxicology Letters, 2008, 183(1-3), 65-71.
发明专利:
1. 王金生, 郭娜, 李剑, 左锐. 一种无机-有机联合改性凹凸棒土吸附剂及其制备方法和其处理氨苄西林废水的方法. 发明专利, ZL 2014 1 0222960.2
2. 李剑, 王金生, 郭娜, 左锐. 一种无机-有机联合改性凹凸棒土吸附剂及其制备方法和其处理6-氨基青霉素烷酸废水的方法. 发明专利, ZL 2014 1 0222456.2
3. 王金生, 李剑, 孙丹妮. 一种镁改性凹凸棒石吸附剂及其制备方法和应用. 发明专利, ZL 201210063541.X.
4. 王金生, 李剑, 孙丹妮. 一种镁改性凹凸棒石吸附剂处理含铯废水的方法. 发明专利, ZL 201210063145.7
5. 李剑, 王金生, 鲍文菊, 滕彦国, 左锐. 一种铁改性凹凸棒石吸附剂处理金霉素废水的方法. 发明专利, ZL 201010582338.4.
6. 李剑, 王金生, 鲍文菊, 滕彦国, 左锐. 一种铝改性凹凸棒石吸附剂处理四环素废水的方法. 发明专利, ZL 201010582476.2.
7. 王金生, 李剑, 鲍文菊, 滕彦国, 左锐. 一种铁改性凹凸棒石吸附剂处理四环素废水的方法. 发明专利, ZL 201010582346.9.
8. 王金生, 李剑, 鲍文菊, 滕彦国, 左锐. 铝改性凹凸棒石吸附剂及其制法和应用. 发明专利, ZL 201010582513.X
9. 王金生, 李剑, 鲍文菊, 滕彦国, 左锐. 一种铝改性凹凸棒石吸附剂处理多西环素废水的方法. 发明专利, ZL 201010582486.6
10. 王子健, 李剑, 马梅, 饶凯锋. 用于检测环境样品中类雌激素化合物的双杂交酵母hER- GRIP1生物测试方法. 发明专利, ZL 200710308509.2
11. 王子健, 李剑, 马梅, 饶凯锋. 用于检测环境中类/抗甲状腺激素化合物的双杂交酵母以及生物测试方法. 发明专利, ZL 200710308507.3
12. 王子健, 李剑, 马梅, 饶凯锋. 用于检测环境中类/抗维甲酸化合物的双杂交酵母以及生物测试方法. 发明专利, ZL 200710308511.X
研究项目:
参加国家重点研发计划子课题:场地污染物监测筛选技术研究 (2018-2022)
参加国家自然科学基金重点项目:地下水位恢复对水质的影响过程与机理研究(2019-2023)
参加国家水体污染控制与治理科技重大专项:松花江傍河取水水质安全保障关键技术及示范课题(2014-2018)
主持环境保护部对外合作项目:意大利国别环境环保研究(2014-2015)
主持北京市青年英才计划项目:胰岛素分泌干扰化合物体外高通量筛选方法研究(2013-2015)
主持北京师范大学自主科研基金项目:重金属化合物甲状腺激素干扰效应及作用机制研究(2013-2014)
主持国家自然科学基金项目:北京官厅水库水、沉积物甲状腺激素干扰毒性诊断(2011-2013)
参加环保公益性行业科研专项:区域地下水污染监测系统与风险管理关键技术研究(2010-2013)
主持环境保护部合作项目:突发环境事件案例分析(2010-2011)
主持中意环保合作项目:应用遥感技术对油/化学品溢漏进行预防、评估与管理项目二期(2009-2011)
参加北京市地下水资源安全评价及污染防控技术研究与示范项目:地下水循环再生能力与水质变化对供水安全的影响研究 (2009-2011)
参加国家水体污染控制与治理科技重大专项:饮用水源地保护与管理技术研究与示范课题(2009-2011)
参加汶川特大地震灾后环境安全评估与应对措施项目:土壤污染评估及应对措施(2008-2010)
参加国家水体污染控制与治理科技重大专项:松花江沿岸地下水污染控制关键技术及工程示范(2008-2010)